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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLN1
All Species:
13.64
Human Site:
T2257
Identified Species:
33.33
UniProt:
Q9Y490
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y490
NP_006280.3
2541
269767
T2257
L
L
D
H
V
L
L
T
L
Q
K
P
S
P
E
Chimpanzee
Pan troglodytes
XP_001173465
2543
271676
I2259
L
L
E
H
V
L
V
I
L
Q
K
P
T
P
E
Rhesus Macaque
Macaca mulatta
XP_001084941
2455
260897
N2239
H
Y
G
R
E
C
A
N
G
Y
L
E
L
L
D
Dog
Lupus familis
XP_531990
2541
269745
T2257
L
L
D
H
V
L
L
T
L
Q
K
P
S
P
E
Cat
Felis silvestris
Mouse
Mus musculus
P26039
2541
269815
T2257
L
L
D
H
V
L
L
T
L
Q
K
P
N
P
D
Rat
Rattus norvegicus
NP_001034114
2541
269654
T2257
L
L
D
H
V
L
L
T
L
Q
K
P
N
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P54939
2541
271823
I2256
L
L
E
H
V
L
V
I
L
Q
K
P
T
H
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001009560
2538
270620
I2252
L
L
E
H
V
L
V
I
I
Q
K
P
S
H
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_391944
2484
265783
K2153
T
L
P
P
I
S
R
K
I
A
Q
S
V
T
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785184
2554
274185
N2273
L
L
E
Q
V
H
S
N
I
Q
K
P
L
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76
95.2
99.2
N.A.
98.6
98.6
N.A.
N.A.
89
N.A.
83
N.A.
N.A.
53.3
N.A.
59.7
Protein Similarity:
100
88.4
95.7
99.7
N.A.
99.5
99.5
N.A.
N.A.
94.7
N.A.
91.6
N.A.
N.A.
69.8
N.A.
75.4
P-Site Identity:
100
73.3
0
100
N.A.
86.6
93.3
N.A.
N.A.
66.6
N.A.
60
N.A.
N.A.
13.3
N.A.
53.3
P-Site Similarity:
100
93.3
6.6
100
N.A.
100
100
N.A.
N.A.
86.6
N.A.
86.6
N.A.
N.A.
33.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
40
0
0
0
0
0
0
0
0
0
0
0
30
% D
% Glu:
0
0
40
0
10
0
0
0
0
0
0
10
0
0
70
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% G
% His:
10
0
0
70
0
10
0
0
0
0
0
0
0
20
0
% H
% Ile:
0
0
0
0
10
0
0
30
30
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
80
0
0
0
0
% K
% Leu:
80
90
0
0
0
70
40
0
60
0
10
0
20
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
20
0
0
0
0
20
0
0
% N
% Pro:
0
0
10
10
0
0
0
0
0
0
0
80
0
60
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
80
10
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
10
0
0
0
0
10
30
0
0
% S
% Thr:
10
0
0
0
0
0
0
40
0
0
0
0
20
10
0
% T
% Val:
0
0
0
0
80
0
30
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _